Dr. Gregory on NIH Expert Panel

The National Heart Lung and Blood Institute invited Dr. Paula Gregory to participate in an expert panel on Short Term Training on October 1.  The purpose of the panel was to review existing programs and to make recommendations to the NHLBI concerning ways to improve the existing programs and recommendations for new types of programs.  Panelists had expertise in areas ranging from distance learning to training grants and they came from universities from all across the country.


Osofsky Co-Edits Important Two-Volume Handbook on Childhood Trauma

Leslie Capo – Director of Information Services 

Joy D. Osofsky, PhD, Paul J. Ramsay Chair and Professor of Pediatrics and Psychiatry at LSU Health New Orleans School of Medicine, is the co-editor of a new two-volume handbook being called a must-read for families, those who work with children, and policymakers. “Violence and Trauma in the Lives of Children,” Praeger Publishers, ABC-CLIO, 2018, edited by Joy D. Osofsky and Betsy McAlister Groves, details the implications of the types of traumas that occur at the individual, family, community, and national levels on children, as well as strategies to build resilience.  Children are rarely at the forefront of people’s minds when violence occurs, whether it be on the streets of cities, in rural communities, or in homes. The volumes explore the significant influence the increasing exposure to violence and trauma has on children’s development, longer-term impacts over time, as well as how to best respond to improve their lives. 

The handbooks explain the neurological, emotional, and behavioral impacts of violence and trauma experienced by newborns, infants, children, and teenagers. They detail the effects of a range of types of violence and trauma, including child abuse, sexual abuse, family violence, teen dating violence, loss of parent or caregiver, exposure to natural disasters, and more. The editors share mental health interventions and treatment strategies to encourage resilience and posttraumatic growth. 

The editors stress that it is very important to raise awareness about the impact of violence and trauma on children including interventions and treatment strategies that are helpful.  Many people avoid talking about violence with children thinking that if it is not talked about or discussed in front of or with children, it will “go away.” Others talk openly about the violence or traumatic events ignoring children who are hearing their discussions, believing that the children won’t be listening and, that if they hear, they won’t pay attention or understand what is being said. 

The handbooks are being lauded by pediatricians, psychiatrists, child stress professionals and judges evidenced by the following reviews on Amazon.com. 

Agili-C IDE Pivotal Study

Leslie Capo
Director of Information Services

CartiHeal, developer of Agili-C, a proprietary implant for the treatment of joint surface lesions, and two LSU Health New Orleans orthopaedic surgeons announced today the successful enrollment of the first two US patients in the Agili-C IDE pivotal study. The first two cases in the United States were performed by Principle Investigator Dr. Vinod Dasa, Associate Professor and Director of Orthopaedic Research, and Dr. Michael Hartman, Associate Professor of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, on August 14, 2018.

The first patient who was randomized to receive an Agili-C implant in the US is a 53-year-old male.  He suffered from a chronic painful cartilage lesion in the trochlea’s center and received a single implant in a mini-arthrotomy approach.

“Currently we lack good treatment options for patients who experience persistent knee pain due to cartilage problems and are too young for knee replacement” said Dr. Dasa. “The Agili-C implantation was smooth without complications. We plan to enroll more patients in the upcoming weeks and hope that this IDE trial finds that the Agili-C implant alleviates pain in these patients, allowing them to return to an active lifestyle.”

In Europe and Israel, 80 patients have already been enrolled and treated in the study, which will include a minimum of 250 patients in US and OUS centers, aiming for an FDA PMA application. The trial’s objective is to demonstrate the superiority of the Agili-C implant over surgical standard of care (microfracture and debridement) for the treatment of cartilage or osteochondral defects, in both arthritic knees and knees without degenerative changes.

Nir Altschuler, Cartiheal’s founder & CEO said, “We would like to congratulate Dr. Dasa and Dr. Hartman for enrolling the first two US patients. This is a significant milestone for our company and for our study. We are very pleased with the enrollment rate to date, and plan to open more US sites in the near future.”

CartiHeal’s cell-free, off-the-shelf implant is CE marked for use in cartilage and osteochondral defects. Agili-C was implanted in a series of trials conducted in leading centers in Europe and Israel, in over 400 patients with cartilage lesions in the knee, ankle and great toe. In these trials, the implant was used to treat a broad spectrum of cartilage lesions, from single focal lesions to multiple and large defects in patients suffering from osteoarthritis.

For more information about the Agili-C IDE study at LSU Health New Orleans, contact Cara Rowe, MSW, CCRP, Orthopaedics Clinical Research Coordinator at 504-568-4640.


Dr. Angela McLean Featured in New Orleans Magazine 

Yet another of LSU SOM exceptional clinicians and educators is featured in New Orleans magazine.  Angela McLean, M.D., Professor in the Department of Medicine and Co-Director of the Clinical Curriculum in the Office of Undergraduate Medical Education was highlighted in the August issue of New Orleans magazine for her savvy handling of a difficult patient case.  You can read the entire story here.




Tsien Named New Orleans Magazine Top Female Achiever 

FernTsien.jpgEach year New Orleans Magazine profiles women from the community who continue to make a difference.  This year, Fern Tsien, Ph.D. (Department of Genetics) was honored to be named one of these women.   

Dr. Tsien received this honor partly because of her research into the genetic causes of hearing loss in the Louisiana Acadians and Mexican Mayan populations.  Her research has been presented to local, national and international audiences and may ultimately lead to unlocking new diagnostic tests or therapies for deafness caused by genetic mutations.  

In addition to her research, Tsien provides extensive community outreach programs to regional schools.  She serves as the co-director of the Science Youth Initiative (SYI) program, which works to engage local elementary and high school students in the sciences. Enlisting the help of medical students and public health graduate students, SYI works with schools to reinforce lessons through hands-on experiments.  The SYI creates a wider exposure to science while raising standardized test scores in science.  

She also provides programs for middle and high school students where they are provided the chance to spend a day at LSU doing STEM experiments with academics.  The goal of SYI’s work is to create a pipeline for the third part of the program which includes paid, eight-week summer internships for high school students, many of whom advance to college and science or health-related careers. 

Congratulations Dr. Tsien! 

Patricia Molina Receives RSA Award 

Congratulations go out to Patricia Molina, M.D/Ph.D. (Department Chair, Physiology) for being awarded the 2018 Seixas Award from the Research Society for Alcohol (RSA).  Dr. Molina received this award for her dedicated service to the RSA, her history of outstanding research, her dedication to training young scientists, and her administrative excellence. 



Lefer To Lead International Heart Research Society Section 

Leslie Capo, Director of Information Services 


David Lefer, PhD, Director of LSU Health New Orleans’ Cardiovascular Center of Excellence, was inaugurated as President-Elect of the International Society of Heart Research – North American Section at its 37th Annual Conference in Halifax, Nova Scotia. He will serve a three-year term before assuming the presidency. 

 According to the Society, the mission of the International Society of Heart Research is to promote the discovery and dissemination of knowledge in the cardiovascular sciences on a worldwide basis through publications, congresses and other media. Membership has grown to include more than 3,000 members. The Society has seven sections – North American, Australasian, Chinese, European, Indian, Japanese and Latin American. 

 Dr. Lefer, who is also a professor of pharmacology, has been working in the fields of myocardial protection and coronary physiology for more than 20 years. He is an internationally recognized leader in understanding the role of nitric oxide and other nitrogen oxide-metabolites in ischemia-reperfusion injury to the heart. His laboratory was among the first to demonstrate the profound loss of endothelial cell-derived nitric oxide from the coronary circulation following coronary artery occlusion and reperfusion.  Lefer’s laboratory was the first to report on the potent cardioprotective actions of nitric oxide in acute myocardial infarction and congestive heart failure.  Several nitrite therapies are currently in clinical trials in the United States and Europe.  In 2005, Lefer’s laboratory began studying the potential cytoprotective actions of a second gaseous signaling molecule – hydrogen sulfide (H2S).  Lefer’s laboratory was also among the first to demonstrate that H2S helps prevent or limit damage in acute myocardial infarction and heart failure model systems.